Firming Serum Booster with Progeline

Progeline is Trifluoroacetyl Tripeptide-2, used at 0.5 to 2% for the look of a firmer jawline, neck and jowl area. It is the peptide formulators reach for when the concern is slackness rather than lines.

This is a formulation ingredient, not a finished serum. Do not apply it undiluted.

What is in the bottle

INCI: Glycerin, Water (Aqua), Dextran, Trifluoroacetyl Tripeptide-2

Four ingredients. Glycerin is a humectant; dextran is a polysaccharide that gives the solution body and makes it blend cleanly. Both are carriers — the active is the tripeptide.

Vegan, paraben-free, fragrance-free, cruelty-free. 0.5 oz blue glass dropper bottle.

The science: Progeline and progerin

Progeline is a biomimetic peptide developed around progerin — a protein that accumulates in cells over time and is studied in connection with cellular ageing. The supplier's research programme is built on that relationship, which is why Progeline is grouped with the firming peptides rather than the line-focused ones.

In a topical formula, it is used for the appearance of firmer, better-defined contours along the jaw and neck.

The supplier's findings describe testing of the raw material. What you see depends on the concentration you use, your base, and how consistently you apply it.

How much to add

Recommended usage rate is 0.5 to 2%. Using our house rate of 9 drops per 1% per fluid ounce:

Full conversions on the serum booster chart.

Where to use it

Progeline is used on the areas where skin looks slack rather than lined:

• Jawline and jowls — the most common reason people buy it
• Neck — works down from the jaw
• Around the eyes — for the look of a lifted lid and firmer under-eye
• Chest — an area that takes a lot of sun and gets forgotten

How to use it

1. Choose a water-based serum, moisturiser or cream. Hyaluronic acid serum is the usual base — 18 drops into 1 oz gives you 2%.
2. Cap and shake well, or stir it through if you are working into a cream.
3. Refrigerate what you are not using.
4. Apply morning and night to the jaw, neck and chest. Use upward strokes.

What to pair it with

For firmness, Progeline layers with Pepha-Tight, Relistase and Uplevity. All four are in the tightening group and work through different routes.

If your concern is expression lines rather than slackness, Argireline is the one you want instead.

Why buy it raw

Finished firming products naming Progeline rarely disclose how much is in them. Blend it yourself at a measured rate and you know — because you counted it in.

Storage

Store at room temperature. The blue glass keeps light out.

For external use only. Cosmetic grade. Do not apply undiluted to skin. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Progeline is a trademark of Lipotec S.A.U.